Product ID:PHENYTOIN SODIUM INJECTION, USP
MSDS Date:06/03/1991
FSC:6505
NIIN:01-211-9769
MSDS Number: BWMHP

ABBOTT LABORATORIES,PHARMACEUTICAL PRODUCTS DIV

14TH AND SHERIDAN RD
NORTH CHICAGO, IL 60064
US

Emergency Phone: 708-937-4372

Info Phone: 708-937-4372/FAX 9823 D. WINFIELD

Cage: 70048

ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV

NORTH CHICAGO, IL 60064-3500 US

Telephone: 847-935-7155

Cage: 70048

PHENYTOIN SODIUM

CAS: 630-93-3

RTECS: MU1400000

ETHYL ALCOHOL (ETHANOL)

CAS: 64-17-5

RTECS: KQ6300000

OSHA PEL 1000 PPM

ACGIH TLV: 1000 PPM; 9394

PROPYLENE GLYCOL

CAS: 57-55-6

RTECS: TY2000000

LD50 LC50 Mixture:ORAL LD50 = 1635 MG/KG (RATS)
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:YES IARC:NO OSHA:NO
Health Hazards Acute and Chronic:PHENTOIN SODIUM IS A RESPIRATORY
IRRITANT, A SKIN IRRITATNT, AN EYE IRRITANT. IT PRODUCES
TERATOGENIC EFFECTS IN ANIMALS. ETHYL ALCOHOL IS KNOWN TO PRODUCE
LIVER INJURY, IS REPORTED TO BE MUTAGENIC AN D IS TERATOGENIC IN
HUMANS.
Explanation of Carcinogenicity:PHENYTOIN SODIUM IS LISTED A S A SUSPECT
HUMAN CARCINOGEN BY NTP BECAUSE IT PRODUCED LYMPHOMAS AND LEUKEMIAS
IN MICE.
Effects of Overexposure:EYE IRRITATION, SKIN IRRITATION, UPPER
RESPIRATORY TRACT IRRITATION.
Medical Cond Aggravated by Exposure:PRE-EXISTING SKIN AND/OR
RESPIRATORY DISORDERS MAY BE AGGRAVATED BY EXPOSURE TO THIS
PRODUCT.

First Aid:EYES: FLUSH WITH WATER FOR 15 MINUTES WHILE HOLDING EYELIDS
OPEN. GET MEDICAL ATTENTION. SKIN: REMOVE CONTAMINATED CLOTHING.
WASH WITH SOAP AND WATER. IF IRRITATION PERSISTS, GET MEDICAL
ATTENTION. IN HALATION: REMOVE TO FRESH AIR. RESTORE BREATHING. GET
MEDICAL ATTENTION. INGESTION: DO NOT INDUCE VOMITING. GET MEDICAL
ATTENTION.

Flash Point Method:OC
Flash Point:54.9F,12.7C*
Lower Limits:NOT GIVEN
Upper Limits:NOT GIVEN
Extinguishing Media:WATER, FOAM, CARBON DIOXIDE
Fire Fighting Procedures:NONE SPECIFIED BY MANUFACTURER.
Unusual Fire/Explosion Hazard:NONE SPECIFIED BY MANUFACTURER.

Spill Release Procedures:ABSORB WITH SUITABLE MATERIAL. FLUSH WITH
WATER.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE IN A COOL, DRY PLACE WITH
ADEQUATE VENTILATION. KEEP AWAY FROM OPEN FLAMES AND HIGH
TEMPERATURES.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.

Respiratory Protection:NOT NORMALLY REQUIRED.
Ventilation:LOCAL EXHAUST AND MECHANICAL (GENERAL) VENTILATION TO
MAINTAIN EXPOSURE LEVELS.
Protective Gloves:RUBBER
Eye Protection:SAFETY GLASSES OR GOGGLES
Other Protective Equipment:AN EMERGENCY EYE WASH STATION AND SHOWER
SHOULD BE AVAILABLE.
Work Hygienic Practices:WASH WITH SOAP AND WATER AFTER HANDLING PRODUCT
AND BEFORE EATING DRINKING OR SMOKING.
Supplemental Safety and Health
* VALUES GIVEN ARE FOR ETHYL ALCOHOL, NOT PRODUCT AS A WHOLE.

HCC:B3
Boiling Pt:B.P. Text:173F,79C*
Melt/Freeze Pt:M.P/F.P Text:NOT GIVEN
Vapor Pres:0.07
Vapor Density:NOT GIVEN
Spec Gravity:1.0306
pH:10-12
Evaporation Rate & Reference:NOT GIVEN
Solubility in Water:PRACTICALLY INSOLUBL
Appearance and Odor:CLEAR LIQUID
Percent Volatiles by Volume:10 %

Stability Indicator/Materials to Avoid:YES
OXIDIZING MATERIALS
Stability Condition to Avoid:HEAT, OPEN FLAME, SPARKS
Hazardous Decomposition Products:TOXIC FUMES OF NITROGEN OXIDES.

Waste Disposal Methods:PREVENT WASTE FROM CONTAMINATING SURROUNDING
ENVIRONMENT. DISCARD ANY PRODUCT, RESIDUE, DISPOSAL CONTAINER OR
LINER IN ACCORDANCE WITH ALL FEDERAL, STATE AND LOCAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.